The gene vdr encodes a transcriptional regulator that regulates the expression of nutritional D-dependent family genes. The protein contains a zinc-finger DNA-binding domain, a transcriptional activation domain and a ligand binding site. The health proteins is a member of the steroid and thyroid junk receptor superfamily.
The T > C allele of the FokI polymorphism on the translation start out site of vdr results in a shortened protein that lacks a practical activation domain. It is characterized by decreased holding to transcribing factor IIB and lowered transactivation activity. The regularity of the version allele differs among cultural groups. It has been implicated in variations in calcium consumption, bone nutrient density (BMD), and anthropometric measurements.
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Venture capitalists and private fairness firms work with VDR software program to create a highly-secure pipe of information with partners, stock portfolio companies, auditors, and businesses. They also utilize platform to handle client documentation linked to investment prospects.